CTC tech benchmarking

Evaluating CTC isolation device performance

Keywords CTC: Circulating tumor cell. Read about what they are and why they’re important here. Leukocyte: White blood cell. Erythrocyte: Red blood cell. I’ve previously discussed how to sort CTCs, and the standards used to characterize device performance. Today, I’ll explain what some of the most common evaluation metrics are, and place them in context of eventual clinical/industrial application. What are common performance criteria? Capture Efficiency is number of target cells captured divided by total number of target cells introduced into the cell isolation system.

Cancer Cell Lines & CTCs: Benchmarking versus Application

x-posted at Kirby Lab Student Blog Keywords Cell Surface Marker: Some protein or receptor sticking out of the cell membrane. I explain this more in depth in my immunocapture post. CTC: Circulating tumor cell. Read about what they are and why they’re important here. Microemboli: A small mass of cells or tissue inside the bloodstream. Platelets: aka thrombocytes, important in the formation of blood clots. Phenotype: Observable characteristics of a cell.