breast cancer

CTC genetic heterogeneity, a window into the metastatic process

x-posted to Kirby Lab Student Blog Keywords BCa: Breast Cancer CTC: Circulating tumor cell. Read about what they are and why they’re important here. Epithelial cell surface marker: A protein or receptor sticking out of the cell membrane of epithelial cells. EMT: Epithelial-to-mesenchymal transition, where cells lose biomarkers associated with their organ of origin and become more stem cell-like. SNR: Signal-to-noise ratio. Tumor genetic heterogeneity has emerged as an effective biomarker of malignant processes1-4.